Blue Light Photodynamic Therapy (PDT) using Levulan Kerastick

What is Levulan Kerastick and Blu-U?

The LEVULAN KERASTICK for Topical Solution plus blue light illumination using the BLU-U Blue Light Photodynamic Therapy (PDT) Illuminator is indicated for the treatment of minimally to moderately thick actinic keratoses of the face or scalp.


This is a 2-step (drug + blue light) treatment designed to treat actinic keratoses (AK) lesions on the face or scalp. AKs are precancerous skin changes caused by chronic sun exposure. If untreated, AKs may develop into skin cancer.

 

What happens during treatment?

1.) In the first part of the treatment, your doctor or other healthcare provider applies LEVU LAN KERASTICK Topical Solution, using the LEVU LAN KERASTICK Topical Solution applicator, to individual AK lesions of the face or scalp.

  • Your provider will specify the time you need to wait in order for the solution to penetrate
  • The label recommends that this period be 14-18 hours

2.) In the second part of the treatment, you will receive BLU-U light treatment.

 

Important Safety Information

Patients should avoid exposure of the photosensitive treatment sites to sunlight or bright light for at least 40 hours after the application of LEVU LAN KERASTICK Topical Solution. Exposure may result in a stinging and/or burning sensation and may cause redness or swelling of the lesions. Sunscreens will not protect against photosensitivity reactions caused by visible light.

Please see additional Important Safety Information on pages 16 and 17.


LEVULAN KERASTICK and BLU-U: a 2-step treatment procedure

Application of LEVUlAN KERASTICK Topical Solution

  • LEVULAN KERASTICK will be uniformly applied to your AK lesions
  • Your provider will direct you to wait the recommended time, per the label, in order to allow the solution to penetrate the targeted cells
  • Avoid exposing the treated lesions to sunlight or bright light for at least 40 hours after application of LEVULAN KERASTICK Topical Solution. Examples include household lights at close range or engaging in outdoor sports or recreation. Sunscreens will not protect against photosensitivity reactions caused by visible light during this time

BLU-U light treatment

  • Before your BLU-U light treatment, the AKs to be treated should be gently rinsed and patted dry
  • Your treatment with the BLU-U will take approximately 17 minutes
  • Protective eyewear should be worn during your BLU-U treatment
  • The BLU-U does not emit UVA or UVB light

The most common side effects include scaling/crusting, skin discoloration, itching, stinging and/or burning, redness and swelling. Severe stinging and/or burning at one or more lesions being treated was reported by at least 50% of patients at some time during the treatment.

Please see additional Important Safety Information on pages 16 and 17.


What should you Expect?

Before treatment starts

  • Be sure to tell your physician if you are taking any oral medications or using any topical prescription or nonprescription products on your face or scalp
  • Bring adequate sun-protective items with you to your appointment, such as a wide-brimmed hat or umbrella

During BlU-U treatment

The BLU-U blue light is of low intensity and will not heat the skin. However, during the light treatment, you may experience sensations of burning, tingling, stinging (sometimes severe), or prickling of the treated AKs. The sensation of stinging and/or burning appears to reach a plateau at 6 minutes into the BLU-U light treatment. These feelings of discomfort should improve at the end of the BLU-U treatment and should subside as early as 1 minute after BLU-U treatment, but may take up to 24 hours after the BLU-U is turned off.

Following treatment, the AKs, and to some degree the surrounding skin, may redden. Swelling and scaling may also occur. However, these effects are temporary and should completely resolve by 4 weeks after treatment. In clinical trials, less than 3% of patients discontinued light treatment due to stinging and/or burning.

After treatment

  • Avoid exposure of your photosensitive treatment sites to sunlight or bright light for at least 40 hours after the application of LEVU LAN KERASTICK Topical Solution
  • Sunscreens will not protect against photosensitivity reactions caused by visible light. Moisturizers may be applied as needed

Ask your doctor whether LEVULAN KERASTICK and BlU-U could be right for you.

The convenience of an in-office treatment:

  • A 2-step treatment procedure that can be completed within 24 hours
  • Low downtime
  • A qualified healthcare professional will administer the treatment
  • No prescription to fill
  • No daily medication to remember
  • Flexible treatment for a range of AKs on face and scalp - Appropriate for either a few or multiple minimally to moderately thick AKs
  • Results include:
  • Recovery beginning right after your treatment with BlU-U blue light ends
  • No scarring reported in clinical trials

Important Safety Information

Patients should avoid exposure of the photosensitive treatment sites to sunlight or bright light for at least 40 hours after the application of LEVU LAN KERASTICK Topical Solution. Both redness and swelling improved by 4 weeks after therapy.

Please see additional Important Safety Information on pages 16 and 17.


Healing Begins When Treatment Ends


The most common side effects include scaling/crusting, skin discoloration, itching, stinging and/or burning, redness, and swelling

  • Both redness and swelling improved by 4 weeks after therapy

Patients may experience a range of reactions to treatment including redness and swelling

Patient 1 following 1 treatment with LEVULAN KERASTICK plus BLU-U

 


Patient 2 following 1 treatment with LEVULAN KERASTICK plus BLU-U

 

 

Contact Us

ACCESS DERMATOLOGY

563 Neff Ave Suite A Harrisonburg, VA 22801

 

16 Ivy Ridge Lane, Suite 138 Fishersville, VA 22939